The National Center of Nuclear Magnetic Resonance of Macromolecules is located at the Federal University of Rio de Janeiro (UFRJ). It is a national NMR facility dedicated to structure and dynamics of proteins and other biomolecules. A 400, 500, 600, 700 and 800 MHz spectrometers are available. CNRMN is the structural branch of the Nucleus for Structural Biology and Bioimaging - CENABIO.
The spectrometers are equipped with four channels system for multidimensional multinuclear analysis, triple resonance inverse probes and cryoprobes.
The 400 and 700 MHz are equipped for solids and biosolids.
The 600 and 800 MHz are equipped for experiments with high hydrostatic pressure.
The facility and the staff has capabilities for:
- Protein structure and dynamics of samples with biological relevance.
- Protein folding studies.
- Structure of nucleic acids and their complex with proteins.
- Structure of complex polysaccharides.
The structure determination of biomolecules is important in basic research and biotechnological development. The importance of the field can be measured by the high impact of structural data in the scientific literature.